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The Humanities Bookstore offers for sale second-hand, new, academic and antiquarian books on the Humanities and Social Sciences and other subjects.
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Edited By Berg,P.A.
Ursodeoxycholic acid (UDCA) has been shown by many studies to be of benefit in the treatment of primary biliary cirrhosis (PBC) and also of primary sclerosing cholangitis (PSC) (and other cholestatic liver diseases), but the mechanism of action of this drug remains obscure and is, in all probability, of multifactorial nature. Possibly, complex interaction of immunomodulatory and membrane-stabilizing effects in conjunction with an altered composition of the bile acid pool are responsible for the beneficial effect. This book, the proceedings of 86th Falk Symposium "Bile Acids and Immunology" (Part 1 of the Basel Liver Week), held in Basel, Switzerland, October 17-18, 1995, starts with an update on important mechanisms involved in autoimmune mediated processes covering the presentation of antigens and autoantigens by professional and non-professional antigen presenting cells, the recognition of the MHC-antigen complex by T-cells, the role of natural and disease-specific antibodies, as well as the control of immune processes via TH1/TH2 cells and their cytokines. It then focuses on the recent findings concerning the aetiopathogenesis of PBC and PSC and the effect of UDCA therapy in these disorders. The most relevant questions which have to be answered in this field are: is the biochemical improvement the consequence of a true antiinflammatory or immunosuppressive effect of UDCA or only due to the replacement of hydrophobic by hydrophilic bile acids?; does UDCA increase the efficacy of immunosuppressive drugs and is it necessary to differentiate between patients who need either a mono-UDCA or a combined (UDCA/steroids) therapy?; are PBC and PSC true autoimmune disorders driven by an autoantigen or only "secondary autoimmune" processes induced by a persisting infectious agent, considering the poor response of both disorders to immunosuppressive treatment as compared to patients with autoimmune hepatitis? This book tries to clarify these problems and open new avenues for further research. It should be of interest to all clinicians and researchers in the field of bile acids. N.B.D/J spine slightly faded with slight mark to base of d/j spine.295pp.
Kluwer Academic Publishers, 1996, Cloth, Book Condition: Like New, Jacket Condition: Very Good. . . 8vo - over 7" - 9" tall.
ISBN: 0792387007
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Inventory #15664
Price: £ 20.00 GBP ($ 24.00 approx. - € 21.20 approx.)
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Edited By Colodny, Robert G.
N.B. Corners of boards and spine bumped. Foxing to foredge of pages. Chipping with some slight loss to corners of D/J and head and tail of D/J spine. Fading to D/J spine. 362pp.
University of Pittsburgh Press, 1966, Cloth, Book Condition: Very Good, Jacket Condition: Good. . . 8vo - over 7" - 9" tall.
ISBN:
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Inventory #29056
Price: £ 12.50 GBP ($ 15.00 approx. - € 13.25 approx.)
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Seitz, Raymond
Raymond Seitz was US ambassador to Britain, 1991-4. Unlike most of his predecessors he didn't return home, but decided to stay, with his wife Caroline and their dogs. "Over Here" (the book has the same title as the radio series) is about the transatlantic relationship, at every level.
Weidenfeld & Nicolson, 1998, Cloth, Book Condition: As New, Jacket Condition: As New. Third Impression. . 8vo - over 7" - 9" tall.
ISBN: 0297815989
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Inventory #28710
Price: £ 7.50 GBP ($ 9.00 approx. - € 7.95 approx.)
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Edited By Macdonald,Thomas T. Etc.
Head of spine and top edge front board slightly bumped.948pp.
Kluwer Academic Publishers, 1990, Cloth/Laminated Boards, Book Condition: Very Good, Jacket Condition: No d/j as Published. . . 8vo - over 7" - 9" tall.
ISBN: 0746201133
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Inventory #15241
Price: £ 95.00 GBP ($ 114.00 approx. - € 100.70 approx.)
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Margerison, Charles; McCann, Dick
Why do some teams win and others lose? This practical guide to building and managing the winning team is based on the method pioneered by the authors. The Margerison/McCann approach has been used and endorsed by a number of major organizations worldwide, including Hewlett Packard, DuPont, Australian Airlines, The Hong Kong Shanghai Bank and Unigate to name a few. Dick McCann is the author of "How To Influence Others at Work". 155pp. N.B. Corners of covers slightly creased. Slight scratch to front cover.
Management Books 2000 Ltd, 1995, Paperback, Book Condition: Very Good, Jacket Condition: No d/j as Published. . . 8vo - over 7" - 9" tall.
ISBN: 1852521147
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Inventory #29036
Price: £ 5.00 GBP ($ 6.00 approx. - € 5.30 approx.)
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