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Category: Science and Technology -> Medicine -> Inventory #15630
In Situ Hybridization: Medical Applications
Edited By Coulton,G.R. And De Belleroche,J.
Book Image
Publisher: Kluwer Academic Publishers
Place: London
Year: 1992
ISBN: 0792389891
Binding: Cloth/Laminated Boards
Size: 8vo - over 7" - 9" tall
Book Condition: Like New
Jacket Condition: No d/j as Published
In situ hybridization has developed as a means of localizing specific DNA and RNA sequences within tissues. The great strength of this approach is the ability to relate the distribution of specific nucleic acids with cell structures and the protein products of the target gene by means of immunohistochemistry. Complementary DNA, RNA or oligo-nucleotide probes, suitably labelled, are hybridized to specific DNA or RNA targets within tissues. The spatial information thus obtained has contributed greatly to our understanding of such diverse areas of research as gene mapping, viral infection, cytogenetics, protein synthesis, prenatal diagnosis and tissue grafting. This book is not intended as another recipe book, although it does describe theoretical and practical aspects of the technology. Rather, the authors critically describe the contribution made by in situ hybridization to specific areas of medical research. 116pp.Slight fade mark to base of spine.
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Price £ 30.00
($ 36.00 approx.)
(€ 31.80 approx.)
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