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Edited By Coulton,G.R. And De Belleroche,J.
In situ hybridization has developed as a means of localizing specific DNA and RNA sequences within tissues. The great strength of this approach is the ability to relate the distribution of specific nucleic acids with cell structures and the protein products of the target gene by means of immunohistochemistry. Complementary DNA, RNA or oligo-nucleotide probes, suitably labelled, are hybridized to specific DNA or RNA targets within tissues. The spatial information thus obtained has contributed greatly to our understanding of such diverse areas of research as gene mapping, viral infection, cytogenetics, protein synthesis, prenatal diagnosis and tissue grafting. This book is not intended as another recipe book, although it does describe theoretical and practical aspects of the technology. Rather, the authors critically describe the contribution made by in situ hybridization to specific areas of medical research. 116pp.Slight fade mark to base of spine.
Kluwer Academic Publishers, 1992, Cloth/Laminated Boards, Book Condition: Like New, Jacket Condition: No d/j as Published. . . 8vo - over 7" - 9" tall.
ISBN: 0792389891
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Inventory #15630
Price: £ 30.00 GBP ($ 39.09 approx. - € 33.15 approx.)
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Edited By Pollitt,R.J. Etc
Proceedings of the 25th Annual Symposium of the SSIEM, Sheffield, UK, Sept. 1987. Combined supplements of Journal of inherited metabolic disease, Vol. II (1988). Embraces many of the major aspects of the study of inborn errors of metabolism.Small mark near spine on base of front board.278pp.
Kluwer Academic Publishers, 1988, Cloth, Book Condition: Very Good, Jacket Condition: No d/j as Published. . . 8vo - over 7" - 9" tall.
ISBN: 074620101x
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Inventory #15236
Price: £ 20.00 GBP ($ 26.06 approx. - € 22.10 approx.)
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Maas, Marnix C.
Molecular imaging techniques enable the visualization of biological processes in living organisms. These techniques rely on synthetic biomolecules ('tracers') that specifically target a physiological process of interest without significantly disturbing it, and that poses some property which allows them to be detected externally. If the detectable property is radioactivity, the molecules are referred to as radiotracers, and the imaging technique is referred to as nuclear imaging. The aims of the research presented in this work are to determine the spatial resolution experimentally, the energy resolution and time resolution attainable with monolithic scintillator detectors, to analyze the dependence of these detector properties on physical quantities such as the scintillator light yield, the APD gain and the noise characteristics of the front-end electronics, and to predict the performance of a small animal PET system based on these detectors. The research presented in this publication is primarily based on experimental work on prototype detector modules. Simulation studies have been carried out in parallel; these are presented elsewhere. Some of the results of these simulation studies are also used in this work. 168pp. N.B. Small crease to bottom corner of rear cover.
IOS Press, 2008, Paperback, Book Condition: Like New, Jacket Condition: No d/j as Published. First Edition. . 8vo - over 7" - 9" tall.
ISBN: 9781586039356
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Inventory #23972
Price: £ 30.00 GBP ($ 39.09 approx. - € 33.15 approx.)
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Hamm, Thomas D.
N.B. Corners slightly creased. Slight bump to bottom edge of front cover. First Midland Book Edition. 261pp.
Indiana University Press, 1992, Paperback, Book Condition: Very Good, Jacket Condition: No d/j as Published. . . 8vo - over 7" - 9" tall.
ISBN: 0253207185
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Inventory #24858
Price: £ 15.00 GBP ($ 19.55 approx. - € 16.58 approx.)
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Brown, Neville
This book is mindful of Geography's big dilemma. How can the subject curb the encroachments of other disciplines: environmental studies, human ecology, political science, geophysics...? The author believes that what we know as 'strategic studies' needs urgently to address a clutch of geography-related considerations customarily seen as outside its remit. Climate change is of singular import, security-wise. Moreover, other pressures on our planetary ecology and resource base, currently appear as critical, taken collectively. Societal and philosophic contradictions are deeply endemic, too, not least within the modern post-industrial nations. Again the attendant security implications may lend themselves well to geographical interpretations. Informing the study throughout will be an awareness of the interactions between Space and Time, addressed not metaphysically but in mundane terms. Then again, while linear distance and bearing are becoming less crucially important, the two-dimensional aspects of geographic space (areas and densities) are becoming more critical. Germane, too, is the medium-term (20 to 30 years) prospect of biowarfare displacing nuclear bombs as the most menacing form of mass destruction. The classical Chinese concept of yin and yang will be examined as lending itself to singularly fruitful application to conflict limitation in an ever-shrinking world. Throughout a distinction is preserved between those questions the author believes can be answered definitively, and those which as yet can only be aired. For both, historical experience will be evaluated in order to give more depth to the interpretation of modern challenges...actual and predicted. Emphasis will be laid on the development of regional associations strong enough to deal with various aspects of a survival strategy: nuclear deterrence, peacekeeping, arms control, developing economic resources, rural and urban ecology. A final review concludes with how one might hope a planetary community can evolve in the longer term - i.e. up to one or two centuries ahead. 386pp.
Sussex Academic Press, 2009, Paperback, Book Condition: Very Good, Jacket Condition: No d/j as Published. First Edition. . 8vo - over 7" - 9" tall.
ISBN: 9781845191702
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Inventory #28840
Price: £ 15.00 GBP ($ 19.55 approx. - € 16.58 approx.)
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