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Edited By Berg,P.A.
Ursodeoxycholic acid (UDCA) has been shown by many studies to be of benefit in the treatment of primary biliary cirrhosis (PBC) and also of primary sclerosing cholangitis (PSC) (and other cholestatic liver diseases), but the mechanism of action of this drug remains obscure and is, in all probability, of multifactorial nature. Possibly, complex interaction of immunomodulatory and membrane-stabilizing effects in conjunction with an altered composition of the bile acid pool are responsible for the beneficial effect. This book, the proceedings of 86th Falk Symposium "Bile Acids and Immunology" (Part 1 of the Basel Liver Week), held in Basel, Switzerland, October 17-18, 1995, starts with an update on important mechanisms involved in autoimmune mediated processes covering the presentation of antigens and autoantigens by professional and non-professional antigen presenting cells, the recognition of the MHC-antigen complex by T-cells, the role of natural and disease-specific antibodies, as well as the control of immune processes via TH1/TH2 cells and their cytokines. It then focuses on the recent findings concerning the aetiopathogenesis of PBC and PSC and the effect of UDCA therapy in these disorders. The most relevant questions which have to be answered in this field are: is the biochemical improvement the consequence of a true antiinflammatory or immunosuppressive effect of UDCA or only due to the replacement of hydrophobic by hydrophilic bile acids?; does UDCA increase the efficacy of immunosuppressive drugs and is it necessary to differentiate between patients who need either a mono-UDCA or a combined (UDCA/steroids) therapy?; are PBC and PSC true autoimmune disorders driven by an autoantigen or only "secondary autoimmune" processes induced by a persisting infectious agent, considering the poor response of both disorders to immunosuppressive treatment as compared to patients with autoimmune hepatitis? This book tries to clarify these problems and open new avenues for further research. It should be of interest to all clinicians and researchers in the field of bile acids. N.B.D/J spine slightly faded with slight mark to base of d/j spine.295pp.
Kluwer Academic Publishers, 1996, Cloth, Book Condition: Like New, Jacket Condition: Very Good. . . 8vo - over 7" - 9" tall.
ISBN: 0792387007
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Inventory #15664
Price: £ 20.00 GBP ($ 25.80 approx. - € 22.10 approx.)
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Zietz, Peer
In 1975, the European Year of Protection of Ancient Monuments, Alsfeld in Upper Hesse acquired model-town status, along with Berlin, Rothenburg ob der Tauber, Xanten and Trier in Germany. In this way the Council of Europe was acknowledging the long tradition of monument protection in a place where an astonishingly large number of historic buildings have survived. There are numerous tightly-packed timber-frame buildings in the medieval ground plan of the town, some built as long ago as the 14th century. The market-place, forming the centre of the town with town hall, Weinhaus (wine house) and Hochzeitshaus (wedding house), is one of the most important complexes of its kind in Germany. The town hall, built in a way that inspired many of its German successors, was to have been pulled down in 1878 by order of the town council. It was not until residents protested that preservation and restoration of what is now the symbol of the town were assured, providing the first example of Alsfeld's tradition in this field. Even today ensembles of unique unity are to be found in its main streets. There is almost nowhere else where one can form such a good impression of a small German medieval town than here. Hesse's Department for the Protection of Monuments was quick to recognize the town's value in terms of architectural history. Art historian Werner Meyer-Barkhausen recorded the historic building stock in the "Alte Stadte" in "Hessen" series as early as 1927. The present volume does not intend to show Alsfeld just as a "timber-frame museum"; an attempt has also been made to show how a town of this kind has changed in the upheavals of the past 100 years by juxtaposing Uwe Rudenburg's photographs with pictures produced around 1880 by Ludwig Bickell, Hesse's first Provincial Conservator. 60pp.
Edition Axel Menges, 1997, Cloth, Book Condition: New, Jacket Condition: New. First Edition. . 4to - over 9" - 12" Tall.
ISBN: 3930698293
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Inventory #20047
Price: £ 18.00 GBP ($ 23.22 approx. - € 19.89 approx.)
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Sanderson, Margaret H.B.
N.B. Head and tail of spine and D/J spine bumped. Previous owners bookplate on ffep. 315pp.
John Donald Publishers Ltd, 1986, Cloth, Book Condition: Very Good, Jacket Condition: Very Good. First Edition. . 8vo - over 7" - 9" tall.
ISBN: 085976110X
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Inventory #23538
Price: £ 10.00 GBP ($ 12.90 approx. - € 11.05 approx.)
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Mud Flower Collective
Previous owner's signature on ffep.226pp.
Pilgrim Press, 1985, Paperback, Book Condition: Good, Jacket Condition: No d/j as Published. . . 8vo - over 7" - 9" tall.
ISBN: 082980546X
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Inventory #28966
Price: £ 5.00 GBP ($ 6.45 approx. - € 5.53 approx.)
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The Worshipful Company of Musicians and Designed By Hawkins, John
No Publication Date. N.B. Two small indentations to front board. 284pp.
The Worshipful Company of Musicians, 0, Cloth/Gilt, Book Condition: Very Good, Jacket Condition: No Jacket. . . 8vo - over 7" - 9" tall.
ISBN: 095371800X
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Inventory #29758
Price: £ 15.00 GBP ($ 19.35 approx. - € 16.58 approx.)
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