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Edited By Berg,P.A.
Ursodeoxycholic acid (UDCA) has been shown by many studies to be of benefit in the treatment of primary biliary cirrhosis (PBC) and also of primary sclerosing cholangitis (PSC) (and other cholestatic liver diseases), but the mechanism of action of this drug remains obscure and is, in all probability, of multifactorial nature. Possibly, complex interaction of immunomodulatory and membrane-stabilizing effects in conjunction with an altered composition of the bile acid pool are responsible for the beneficial effect. This book, the proceedings of 86th Falk Symposium "Bile Acids and Immunology" (Part 1 of the Basel Liver Week), held in Basel, Switzerland, October 17-18, 1995, starts with an update on important mechanisms involved in autoimmune mediated processes covering the presentation of antigens and autoantigens by professional and non-professional antigen presenting cells, the recognition of the MHC-antigen complex by T-cells, the role of natural and disease-specific antibodies, as well as the control of immune processes via TH1/TH2 cells and their cytokines. It then focuses on the recent findings concerning the aetiopathogenesis of PBC and PSC and the effect of UDCA therapy in these disorders. The most relevant questions which have to be answered in this field are: is the biochemical improvement the consequence of a true antiinflammatory or immunosuppressive effect of UDCA or only due to the replacement of hydrophobic by hydrophilic bile acids?; does UDCA increase the efficacy of immunosuppressive drugs and is it necessary to differentiate between patients who need either a mono-UDCA or a combined (UDCA/steroids) therapy?; are PBC and PSC true autoimmune disorders driven by an autoantigen or only "secondary autoimmune" processes induced by a persisting infectious agent, considering the poor response of both disorders to immunosuppressive treatment as compared to patients with autoimmune hepatitis? This book tries to clarify these problems and open new avenues for further research. It should be of interest to all clinicians and researchers in the field of bile acids. N.B.D/J spine slightly faded with slight mark to base of d/j spine.295pp.
Kluwer Academic Publishers, 1996, Cloth, Book Condition: Like New, Jacket Condition: Very Good. . . 8vo - over 7" - 9" tall.
ISBN: 0792387007
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Inventory #15664
Price: £ 20.00 GBP ($ 25.80 approx. - € 22.10 approx.)
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Kelley, Emma Dunham
This novel, which was very popular when published in 1891, tells the story of the conversion experiences of a group of young, middle-class Baptist women and their subsequent - or consequent - marriages. In it, racial issues are only indirectly addressed, gentility is a concern ranking second only to salvation, and humility and obedience are prerequisites to a woman's acceptance by the Christian community. In essence, this is a novel of socialization rather than of social protest.
Oxford University Press, 1992, Paperback, Book Condition: Fine, Jacket Condition: No d/j as Published. . . 16mo - over 5" - 6" tall.
ISBN: 0195075765
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Inventory #27847
Price: £ 9.50 GBP ($ 12.26 approx. - € 10.50 approx.)
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Hyland, Paul
This title is a study in vanity and ambition, madness and resignation. Sir Walter Raleigh was one of the greatest courtiers of his day, Elizabeth's favourite, dashing, brilliant, wily and powerful. This book book takes as its subject his extraordinary last months, during the summer of 1618 when, his last voyage a failure and under great suspicion from James I, he was escorted back to London by Sir Lewis Stucley; the tragi-comic story of this journey, from Plymouth to the scaffold, of Raleigh's grotesque behaviour along the way, of the web of deceit and counter-treachery woven between him and his reviled and much misunderstood betrayer "Judas" Stucley, and of their travelling companion the French physician and double agent Dr Manourie. Around this last journey will be linked the other players in the drama: Bess, Raleigh's handsome, resourceful and distracted wife; Carew, their 13-year-old son; and Samuel King, privateering captain and link with past glories. On countless occasions Raleigh has the opportunity to escape, and refuses it; then, when he at last opts for freedom (in a false beard), he finds himself betrayed again. 242pp.
Harper Collins, 2003, Cloth, Book Condition: Like New, Jacket Condition: Like New. First Edition. . 8vo - over 7" - 9" tall.
ISBN: 0007106009
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Inventory #20974
Price: £ 9.50 GBP ($ 12.26 approx. - € 10.50 approx.)
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Bjrndal, Ivar
152pp. N.B. Two inscriptions on half title page.NORWEGIAN TEXT.
Forum Bjrndal, 2002, Cloth/Laminated Boards, Book Condition: Fine, Jacket Condition: No d/j as Published. Signed First Edition. . 8vo - over 7" - 9" tall.
ISBN: 8299494052
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Inventory #24428
Price: £ 15.00 GBP ($ 19.35 approx. - € 16.58 approx.)
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Walters, Kerry S.
Against the religious backdrop of pre- and postcolonial America stands the towering figure - and mind - of Benjamin Franklin. A Renaissance man in a Revolutionary time, Franklin had interests and knowledge not only in religion but in literature, philosophy, politics, publishing, history, and scientific inquiry, among many other disciplines. Kerry S. Walters examines Franklin's search for the Divine using a similar, multifaceted approach - and in so doing has created the first extended treatment of Franklin's religious thought in thirty years. Walters brings the same intellectual range and depth to the understanding of Franklin's beliefs that Franklin brought to his own quest. What emerges from this pilgrimage into the soul of one of America's greatest figures is a very human Benjamin Franklin who grew with the accumulation of knowledge to arrive at a 'theistic perspectivism', which provided him with a philosophical explanation for the diversity of religious faiths - and a justification for the liberty of conscience he advocated throughout his life. "Benjamin Franklin and His Gods" is an original and beautifully challenging spiritual and intellectual biography. It is destined to be a classic. 213pp. N.B. Fading to spine and spine edge of rear cover. Previous owners inscription to ffep.
University of Illinois Press, 1999, Paperback, Book Condition: Very Good, Jacket Condition: No d/j as Published. First Edition. . 8vo - over 7" - 9" tall.
ISBN: 0252067398
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Inventory #24879
Price: £ 12.50 GBP ($ 16.13 approx. - € 13.81 approx.)
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