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Martin, Glen T.
Inscribed by author on title page dated 6th March 2008. Includes note signed by author written to Errol E. Harris who wrote the preface for this title. 500pp.
Institute for Economic Democracy Press, 2008, Paperback, Book Condition: Good, Jacket Condition: No d/j as Published. Signed Copy. . 8vo - over 7" - 9" tall.
ISBN: 9781933567068
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Inventory #28399
Price: £ 15.00 GBP ($ 18.00 approx. - € 15.90 approx.)
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Hunt,Richard H. And Tytgat,Guido N.J.
The fourth meeting in the series "Helicobacter pylori: Basic Mechanisms to Clinical Cure" was held on the island of Bermuda in late March 2000 and was sponsored by Axcan Pharmaceuticals. This was only some two years after the third meeting in San Diego, and it seemed hardly possible that there would be so much new information. However, as the contributions in this volume testify, there was plenty of new information with important implications for both understanding this infection and for clinical management. Some of this information was of a fundamental nature, such as the role of the acid sensitive urei channel in regulating the influx of urea and the formation of transported ammonia back in the microbial perisplasmic space to neutralize acid; the observation of genetic polymorphism of the IL-1b gene as an explanation of achlorhydria and gastric cancer risk in the first-degree relatives of gastric cancer patients; and the peculiar biochemical and physiological consequences of the genome of the microorganisms. The format of the meeting, with fifteen-minute presentations by world experts closely involved in helicobacter research followed by ample time for panel discussions, was again followed this year. Traditional aspects included detailed study of the microbial characteristics, the novel helicobacters, the interaction with the human host, the peculiarities of the inflammatory immune response, the short and long-term mucosal consequences, the effects on acid secretion, the problem of gastric malignancy, and the therapeutic possibilities. However, a series of short debates was introduced to highlight controversial issues, such as the pathogenic or commensal role of the organism, the role of virulence factors, the characteristics of the inflammatory immune response, the reversibility of mucosal atrophy and metaplasia, and the primary or secondary role of quadruple therapy, to name just a few. This provocative approach was very successful and provided fuel for further in-depth discussions. These debates have been included in this book in the form of conventional manuscripts in order to maintain the shortest possible production time for the publication of the proceed Helicobacter pylori has come a long way since the first meeting in Amelia Island, in 1993, and the science of this organism and the understanding of the consequences of the infection have advanced our knowledge fundamentally and revolutionized our thinking about gastrointestinal disease. We now recognize the existence of more than thirty Helicobacter species, some of which may play a significant role in human disease. The experience gained through our investigation of H. pylori promises to make a significant contribution to the future exploration of the possible role of Helicobacter species in hepatic, biliary, and intestinal diseases. 689pp.N.B.Slight annotation to first few pages.
Kluwer Academic Publishers, 2000, Cloth/Laminated Boards, Book Condition: Very Good, Jacket Condition: No d/j as Published. . . 8vo - over 7" - 9" tall.
ISBN: 0792387643
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Inventory #14961
Price: £ 20.00 GBP ($ 24.00 approx. - € 21.20 approx.)
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Edited By Zglinicki,Thomas Von
During the last 40 years, the study of the biological basis of aging has progressed tremendously, and it has now become an independent and respectable field of study and research. The essential cause of aging is molecular damage that slowly overwhelms cellular and organismic defense, repair and maintenance systems. In recent years, a wealth of highly sophisticated research has transformed this idea from a credible hypothesis not only to a major theory, but essentially to accepted knowledge. "Aging at the Molecular Level" examines the key elements in this transformation. Bringing together contributions from an international team of authors, this volume will be of interest to graduates and postgraduates in the fields of medicine and nursing, researchers of different aspects of biogerontology and those in the pharmaceutical, cosmeceutical, nutraceutical and health-care industry. 248pp.Biology of Aging and Its Modulation Volume 1.
Kluwer Academic Publishers, 2003, Cloth/Laminated Boards, Book Condition: Like New, Jacket Condition: No d/j as Published. First Edition. . 8vo - over 7" - 9" tall.
ISBN: 1402017383
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Inventory #29074
Price: £ 60.00 GBP ($ 72.00 approx. - € 63.60 approx.)
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Lumley, C.E.; Walker, Stuart R.
Regulatory review is the last major development hurdle that must be passed by a new medicine before it reaches the market. At a time when pharmaceutical companies are reviewing their R&D strategies, and attempting to reduce drug development times, it is extremely important that the review process is made as efficient as possible. The 11th CMR Workshop, held in September 1995, provided the opportunity for regulatory authority and industry personnel from Europe, North America, Australia and Japan to openly discuss views and exchange experiences on the subject of improving the review process. The proceedings of this meeting provide a comprehensive overview of the current review process around the world. The contributors describe the present situation and highlight company strategies and regulatory initiatives to improve the review process. This volume also summarises the suggestions that were developed by the participants, covering many facets of this process, including the quality and size of the dossier, dialogue, submission strategies, feedback and the response to questions. 171pp.
Kluwer Academic Publishers, 1996, Cloth/Laminated Boards, Book Condition: Like New, Jacket Condition: No d/j as Published. . . 8vo - over 7" - 9" tall.
ISBN: 0792387066
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Inventory #15643
Price: £ 20.00 GBP ($ 24.00 approx. - € 21.20 approx.)
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Edited By Hadziselimovic,F.
This volume presents the proceedings of the Falk Symposium No. 127 on "Autoimmune Diseases in Paediatric Gastroenterology" (IV International Falk Symposium on Paediatric Gastroenterology), held in Basel, Switzerland, on November 8-9, 2001. The symposium focused on the role of the immune system, both the acquired and the innate systems, in inflammatory bowel disease (IBD) in children and adolescents. The innate system has an important fundamental role in host defence by initiating immune responses against potentially deleterious matter. However, a mutation within the innate system may elicit an immune response against the host: hence, an autoimmune response. Chronic autoimmune hepatitis occurs predominantly in young people, and especially in women. Immunological changes are conspicuous. Tissue antibodies are found in a large number of patients. This is a disease of disordered immunoregulation marked by a deficit in suppressor T cells causing the production of autoantibodies against specific hepatocyte surface antigen. Liver membrane protein is found in the sera of patients with autoimmune chronic acute hepatitis and with primary biliary cirrhosis (PBC).256pp.Slight fade mark to base of d/j spine.
Kluwer Academic Publishers, 2002, Cloth, Book Condition: Like New, Jacket Condition: Like New. . . 8vo - over 7" - 9" tall.
ISBN: 0792387783
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Inventory #14705
Price: £ 20.00 GBP ($ 24.00 approx. - € 21.20 approx.)
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