The Humanities Bookstore.com
You are not logged in   |   Your basket is empty
About Us Inventory Log In Basket Links

Search our stock
Search Type

Categories
 
Welcome to The Humanities Bookstore
The Humanities Bookstore offers for sale second-hand, new, academic and antiquarian books on the Humanities and Social Sciences and other subjects.
By ordering directly from us through our own website here at the Humanities Bookstore you are guaranteed priority service with preferential postage rates cheaper than through any multi dealer site we list on.
You can currently Search our Stock by Title, Author, Keyword or ISBN.
You can also Browse by Category, by clicking on the category you require, you will then be offered one or more sub categories to refine your selection.
Once you log on, or create a new account, you will be able to make orders via our secure server.
Book Image
Edited By Haussinger,D Etc
The hepatocyte adapts its metabolic and excretory function to changes in nutrient supply, xenobiotics, cytokines and hormones, which provides a basis for the role of the liver in the maintenance of the body's homeostasis. Such adaptations of hepatocellular function to the environment require not only structures for recognition of signal molecules and for the sensing of environmental alterations, but also machineries which transfer this information to intracellular effector sites. Considerable progress has been made during recent years with respect to the understanding of membrane-associated receptor systems and the molecular mechanisms by which signals are transduced from these receptors to the effector sites inside the cell, i.e. the nucleus and other organelles, the cytoskeleton and various enzymes. A complex signal transduction network involving a co-ordinated action of a variety of protein kinase and phosphatase cascades has been identified. Such signalling events are not only important for the understanding of the physiological regulation of liver cell function, but also provide new pathophysiological and therapeutic aspects. This text, the proceedings of a Falk Workshop on "Signalling in the Liver" (Part IV of the Liver Week Freiburg 1997) held in Freiburg, Germany, October 6, brings together an international forum of experts in both basic science and clinical applications.Slight fading to base of D/J spine.224PP
Kluwer Academic Publishers, 1998, Cloth, Book Condition: Like New, Jacket Condition: Like New. . . 8vo - over 7" - 9" tall.
ISBN: 0792387449
Add To Basket
Inventory #14908
Price: £ 20.00 GBP ($ 24.40 approx. - € 23.80 approx.)
Book Image
Edited By Lentze,M.J. Etc.
This book reviews the physiological basis of bile formation as well as its ontogenesis. The book aims to describe the most important cholestatic liver diseases in infancy and critically reviews treatment modalities of cholestatic liver diseases: surgical, medical, new and old. The book addresses paediatricians and hepatologists, as well as basic scientists interested in bile acid metabolism and its derangements in cholestatis. This is the proceedings of the Falk Symposium No. 63 "Pediatric Cholestasis": Novel Approaches to Treatment" held in Titisee, Germany, October 9-10, 1991. N.B.D/J spine slightly faded with slight mark to base of d/j spine.370pp.
Kluwer Academic Publishers, 1992, Cloth, Book Condition: Like New, Jacket Condition: Very Good. . . 8vo - over 7" - 9" tall.
ISBN: 0792389778
Add To Basket
Inventory #15673
Price: £ 20.00 GBP ($ 24.40 approx. - € 23.80 approx.)
Book Image
Edited By Wolstenholme, G.E.W
Previous owners inscription on ffep. Some staining to top edge of boards. Head and tail of spine rubbed. D/j chipped and has tears to the edges and corners. d/j is marked. 495pp.
J & A Churchill Ltd., 1960, Cloth, Book Condition: Good, Jacket Condition: Poor. First Edition. . 8vo - over 7" - 9" tall.
ISBN:
Add To Basket
Inventory #21448
Price: £ 10.00 GBP ($ 12.20 approx. - € 11.90 approx.)
Book Image
Stone, T.W.; Simmonds, H.A.
Head of spine slightly bumped. Slight fade mark to base of spine.257pp.
Kluwer Academic Publishers, 1991, Cloth/Laminated Boards, Book Condition: Very Good, Jacket Condition: No d/j as Published. . . 8vo - over 7" - 9" tall.
ISBN: 0792389255
Add To Basket
Inventory #15609
Price: £ 30.00 GBP ($ 36.60 approx. - € 35.70 approx.)
Book Image
Hepatocellular carcinoma (HCC) and cholangiocarcinoma (CC), both increasing in incidence, have become a major topic of basic and clinical research as well as clinical practice in hepatology. Experts in the field update the current concepts on the carcinogenesis of HCC and CC such as genetic alterations in the pathways of cell cycle and apoptosis regulation, the hypothesis of dedifferentiation of hepatocytes to the malignant phenotype vs that of activation of hepatic progenitor cells incapable of maturation (maturation arrest hypothesis). In spite of an increasing number of genetic alterations described in human HCC as well as cell regulatory pathways tested in experimental HCC models, the key hits causing progression of the cell cycle in imbalance with apoptosis, tissue invasive growth and metastatic potential of cell clones still remain elusive. Very powerful genomic and proteomic techniques are promising insights into the carcinogenesis of liver malignancies that will allow more efficient therapeutic strategies. The current concepts on risk profiling, surveillance of risk groups and therapeutic strategies are evidence-based for HCC and less detailed for CC. Surveillance of risk groups improves detection of liver tumours in curable stages. Best strategies for curative treatment of HCC use neoadjuvant antitumour therapies before liver transplantation and a role is emerging for living donor-related liver transplantation. New palliative therapies for HCC are in the experimental stage with biological response modifiers, including angiogenesis inhibitors, and entering phase II clinical trials with the alpha-fetoprotein derived vaccines.211pp.N.B.Slight fade mark to base of d/j spine.
Kluwer Academic Publishers, 2002, Cloth, Book Condition: Like New, Jacket Condition: Like New. . . 8vo - over 7" - 9" tall.
ISBN: 0792387791
Add To Basket
Inventory #14692
Price: £ 40.00 GBP ($ 48.80 approx. - € 47.60 approx.)
The Humanities Bookstore is a specialist internet department of Fireside Bookshop , based at 1 The Arcade, High Street, Littlehampton, West Sussex, BN17 5AB, U.K.
For more information and any enquiries, you can email us at info@thehumanitiesbookstore.com or phone +44 (0)1903 721985.